No, the series is not a reboot of the movie or of the Limitless series. However, considering the title, we could have seen a link. But in this case, we are a thousand miles away from the little magic pills! Let's go to the 16ème century!
Yes, because the series has a historical accent since it follows the adventures of Magellan. Magellan is not only a strait. It is also and above all an outstanding Portuguese navigator. He was the first to embark on a circumnavigation, in other words, to sail around the world.
Contrary to what one might think at the time, people were well aware that the Earth was round. But nobody had yet ventured to go around it. Especially because of technical (the ships) and logistical problems (the need to make stopovers, to make repairs and to have food). Magellan's objective was far from being disinterested. On the other side of the world, there was a place (the Moluccas, today's Indonesia) known as the island of spices. At the time, Europe was very fond of spices. It was therefore necessary to develop new shipping routes.
The series Without Limits transports us in this epic journey throughout the episodes. However, it does not ignore the dramas and bad lucks experienced by the crew. Magellan himself will die before finishing his world tour.